C57BL/6JNifdc-Ptprctm1(K302E)Bcgen/Bcgen • 112593
| Product name | B-CD45.1 mice |
|---|---|
| Catalog number | 112593 |
| Strain name | C57BL/6JNifdc-Ptprctm1(K302E)Bcgen/Bcgen |
| Strain background | C57BL/6JNifdc |
| NCBI gene ID | 19264 (Mouse) |
| Aliases | loc; B220; Cd45; L-CA; Ly-5; T200; CD45R; Lyt-4 |
Gene targeting strategy for B-CD45.1 mice. Introduce a lysine to glutamic acid mutation (K302E) in mouse Ptprc gene, resulting the encoding protein can be recognized by anti-CD45.1 antibodies
CD45.1 expression analysis in homozygous B-CD45.1 mice by flow cytometry. Spleen, blood and bone marrow were collected from wild-type C57BL/6 mice (+/+) and homozygous B-CD45.1 mice (Mut/Mut), and then analyzed by flow cytometry with anti-CD45.1 or CD45.2 antibodies. CD45.2 was detection in C57BL/6 mice. CD45.1 were only detectable in B-CD45.1 mice but not in wild-type mice.
