• 德晋贵宾厅

    B-hADRB1 mice

    C57BL/6N-Adrb1tm1(ADRB1)Bcgen/Bcgen • 111897

    B-hADRB1 mice

    Product nameB-hADRB1 mice
    Catalog number111897
    Strain nameC57BL/6N-Adrb1tm1(ADRB1)Bcgen/Bcgen
    Strain backgroundC57BL/6N
    NCBI gene ID153 (Human)
    AliasesRHR; B1AR; FNSS2; ADRB1R; BETA1AR

    在此页面上

    • Phenotypic analysis

    海报

    查看全部

      发表文章

        mRNA expression analysis
        Strain specific analysis of ADRB1 mRNA expression in wild-type C57BL/6 mice and B-hADRB1 mice by RT-PCR. Liver RNA were isolated from wildtype C57BL/6 mice (+/+) and homozygous B-hADRB1 mice (H/H), then cDNA libraries were synthesized by reverse transcription, followed by PCR with mouse or human ADRB1 primers. Mouse Adrb1 mRNA was detectable only in wild-type C57BL/6 mice. Human ADRB1 mRNA was detectable only in homozygous B-hADRB1 mice but not in wild-type mice.
        Protein expression analysis

        Western blot analysis of ADRB1 protein expression in homozygous B-hADRB1 mice. Various tissue lysates were collected from C57BL/6N wild-type mice (+/+) and homozygous B-hADRB1 mice (H/H), and then analyzed by western blot with anti-ADRB1 antibody. 40 μg total proteins were loaded for western blotting analysis. ADRB1 was detectable in heart, liver and brain of homozygous B-hADRB1 mice. The protein expression level of ADRB1 was relatively low in the lung and kidney of homozygous B-hADRB1 mice.

        * When publishing results obtained using this animal model, please acknowledge the source as follows: The animal model [B-hADRB1 mice] (Cat# 111897) was purchased from Biocytogen.